1
speak familiarly to/with sb
familiarly 修饰 speak，表示态度亲密、不拘礼节；to 更强调对象，with 更强调互动。
She spoke familiarly with her colleagues.
她和同事们说话很随意。
亲密地；不拘礼地；随意地
先理解核心含义，再看它在真实句子里的用法。
亲密地；不拘礼地；随意地
in an intimately familiar manner
She spoke familiarly with her colleagues.
她和同事们说话很随意。
不拘礼节地
With a lack of formality:
熟悉地；精通地
With knowledge or experience:
She smiled at me familiarly, as if we had known each other for years.
她亲密地对我微笑，仿佛我们已经认识多年。
The old friends chatted familiarly over coffee.
老朋友们一边喝咖啡一边不拘礼地聊天。
He greeted the guests familiarly, calling everyone by their first name.
他随意地跟客人打招呼，直呼每个人的名字。
familiarly 修饰 speak，表示态度亲密、不拘礼节；to 更强调对象，with 更强调互动。
She spoke familiarly with her colleagues.
她和同事们说话很随意。
此结构常用被动，后接别名或俗称，familiarly 修饰 known，表示广为人知的亲昵称呼。
The dish is familiarly known as comfort food.
这道菜被亲切地称为“安慰食物”。
refer to ... as ... 表示称呼，加入 familiarly 体现熟络、随意的语气。
They referred to the old house familiarly as the castle.
他们亲昵地把那栋老房子叫作“城堡”。
Not this
He greeted me very familiar.
Use this
He greeted me very familiarly.
`familiar` 是形容词，不能修饰动词 `greeted`；修饰动作要用副词 `familiarly`。中文的“熟悉地”在英文中对应副词，需用 -ly 形式。
Not this
I am familiarly with him.
Use this
I am familiar with him.
`be familiar with` 是固定搭配，表示“熟悉某人/某物”；`familiarly` 是副词，不能作 `be` 的表语。这里要用形容词 `familiar`。
Focus on the distinctions below. Other candidates are kept compact until a reliable usage note is available.
俗称；通常叫做
The plant is familiarly known as the money tree.
这种植物俗称发财树。
亲密地交谈；不拘礼地说话
They spoke familiarly about their school days.
他们亲密地谈起学生时代。
随意对待某人；对某人毫不拘礼
He treated his students familiarly, which made the classroom relaxed.
他对待学生很随意，这使课堂气氛轻松。
亲密地称呼某人；不拘礼地称呼某人
She addressed the celebrity familiarly by his nickname.
她亲密地用昵称称呼那位名人。
通俗地称为，俗称
The plant, familiarly known as the Venus flytrap, catches insects.
这种植物俗称捕蝇草，会捕捉昆虫。
通俗地说，简单来说
To put it familiarly, the plan is a total mess.
通俗地说，这个计划一团糟。
Use familiarly naturally, then get feedback on meaning, tone, grammar, and phrasing.
Revisit a common error or keep this word in your review list.
熟悉（familiar）地→亲密随意，像老朋友一样不拘礼。
语域：formal 常见场景：正式写作、文学性叙述 familiarly 多用于正式或文学性语境，表示以亲密、不拘礼的方式；口语中较少使用。
None of these is a perfect rhyme with familiarly /fəˈmɪljərli/. The closest spelling match, peculiarly /pɪˈkjuːljərli/, also ends in -liarly and keeps the /ljərli/ tail, but its stressed vowel is /uː/ instead of /ɪ/. Particularly, similarly, and regularly look similar on paper, yet their stressed vowels or following consonants do not match, so do not treat them as rhymes.
Dictionary facts from ECDICT, WIKTIONARY.