1
have/has + past participle + up to now
通常与现在完成时连用。
We have received no complaints up to now.
到目前为止，我们没有收到任何投诉。
到目前为止；至今
先理解核心含义，再看它在真实句子里的用法。
到目前为止；至今
Until now; as of now.
We have received no complaints up to now.
到目前为止，我们没有收到任何投诉。
到目前为止。
Until now; as of now.
Up to now, I have finished three chapters of the book.
到目前为止，我已经完成了这本书的三章。
She has been very busy with work up to now, but she is going on vacation next week.
到目前为止她一直忙于工作，但下周她要去度假。
Up to now, we have not received any reply from the company.
到目前为止，我们还没有收到公司的任何回复。
通常与现在完成时连用。
We have received no complaints up to now.
到目前为止，我们没有收到任何投诉。
She has been working here up to now.
到目前为止，她一直在这里工作。
置于句首时，常带逗号。
Up to now, everything has gone smoothly.
到目前为止，一切进展顺利。
Not this
I didn't finish the work up to now.
Use this
I haven't finished the work up to now.
“到目前为止”常与现在完成时连用，表示从过去持续到现在的状态或动作，而一般过去时表示过去的动作，与“up to now”不兼容。
Not this
From up to now, we have made progress.
Use this
Up to now, we have made progress.
“up to now”本身已包含“从过去到现在”的含义，无需再加“from”，否则语义重复。
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Dictionary facts from ECDICT, WIKTIONARY.